CD46 anticorps (AA 35-313)

N° du produit ABIN5776214

Cet anticorps anti-CD46 est un anticorps Souris Monoclonal détectant CD46 dans WB, FACS, ELISA, IHC, IF et ICC. Adapté pour Humain.

Aperçu rapide pour CD46 anticorps (AA 35-313) (ABIN5776214)

Antigène: CD46

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD46 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AT2G9

Détail du produit anti-CD46 anticorps

Épitope: AA 35-313

Immunogène: Recombinant human CD46 (35-313aa) purified from E. coli

Isotype: IgG2a kappa

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Détails sur CD46

Antigène: CD46

Autre désignation: CD46

Sujet: Membrane Cofactor Protein (CD46) is a type 1 membrane protein that plays an important inhibitory role in the complement system. CD46 regulates the complement cascade by inhibiting C3b and C4b deposited on self tissue. This protein is a cofactor that binds to C3b and C4b, allowing their degradation by a plasma serine protease called factor I. This function resides in the complement control protein repeats (CCPs), with CCP1-4 essential for regulation. CD46 is implicated in the development and/or progression of selected cancer types.

NCBI Accession: NP_758860

Pathways: Regulation of Actin Filament Polymerization