PDIA3 anticorps (AA 25-505)
Aperçu rapide pour PDIA3 anticorps (AA 25-505) (ABIN5776230)
Antigène
Voir toutes PDIA3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Épitope
- AA 25-505
-
Fonction
- Human GRP58/PDIA3 antibody
-
Purification
- Purified
-
Immunogène
- Recombinant human PDIA3 (25-505aa) purified from E. coli
-
Isotype
- IgG2a kappa
-
-
-
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C,-20 °C,-80 °C
-
Stockage commentaire
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
-
-
- PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))
-
Autre désignation
- GRP58/PDIA3
-
Sujet
- PDIA3, also known as protein disulfide-isomerase A3, is a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. This protein has protein disulfide isomerase activity. PDIA3 is also part of the major histocompatibility complex (MHC) class I peptide-loading complex (TAP1), which is essential for formation of the final antigen conformation and export from the endoplasmic reticulum to the cell surface.
-
NCBI Accession
- NP_005304
-
Pathways
- Maintenance of Protein Location, Protein targeting to Nucleus, Cell RedoxHomeostasis
Antigène
-