PGAM2 anticorps (AA 1-253)

N° du produit ABIN5776232

Cet anticorps anti-PGAM2 Monoclonal Souris (Clone AT5A7) (ABIN5776232) détecte spécifiquement PGAM2 dans WB, IF, ELISA et ICC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour PGAM2 anticorps (AA 1-253) (ABIN5776232)

Antigène: PGAM2 (phosphoglycerate Mutase 2 (Muscle) (PGAM2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PGAM2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)

Clone: AT5A7

Détail du produit anti-PGAM2 anticorps

Épitope: AA 1-253

Fonction: Human PGAM2 antibody

Purification: Purified

Immunogène: Recombinant human PGAM2 (1-253aa) purified from E. coli

Isotype: IgG2b kappa

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing cycles

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Détails sur PGAM2

Antigène: PGAM2 (phosphoglycerate Mutase 2 (Muscle) (PGAM2))

Autre désignation: PGAM2

Sujet: Phosphoglycerate mutase (PGAM) catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. Since both 3-PGA and 2-PGA are allosteric regulators of the pentose phosphate pathway (PPP) and glycine and serine synthesis pathways, respectively, PGAM2 may contribute to the biosynthesis of amino acids, 5-carbon sugar, and nucleotides precursors. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). Mutations in this gene cause muscle phosphoglycerate mutase deficiency, also known as glycogen storage disease X. PGAM2 is one of two PGAM subunits found in humans and is predominantly expressed in adult muscle.

NCBI Accession: NP_000281