TBC1D4 anticorps (pThr642)
Aperçu rapide pour TBC1D4 anticorps (pThr642) (ABIN5955761)
Antigène
Voir toutes TBC1D4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pThr642
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Specificité
- Acrg embryonic lethality (mouse) minimal region ortholog,Acrg embryonic lethality minimal region ortholog,Acrg embryonic lethality mouse minimal region ortholog,Akt substrate of 160 kDa,AS 160,AS160,BUB2,CDC16,KIAA0603,NIDDM5,TBC (Tre 2 BUB2 CDC16) domain containing protein,TBC Tre 2 BUB2 CDC16 domain containing protein,TBC1 D4,TBC1 domain family member 4,Tbc1d4,TBCD4,Tre-2
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Purification
- Affinity purification
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Immunogène
- Synthesized peptide derived from human TBC1D4 around the phosphorylation site of Thr642
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Isotype
- IgG
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Indications d'application
- WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- TBC1D4 (TBC1 Domain Family, Member 4 (TBC1D4))
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Autre désignation
- TBC1D4
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Sujet
- TBC1 domain family member 4 (TBC1D4), also designated AS160, can be insulin- and/or AKT1-induced. Insulin-stimulated phosphorylation is required for GLUT4 translocation. TBC1D4 may play a role as a GTPase activating protein for proteins in the Rab family. It is expressed primarily in skeletal muscle and heart, as well as spleen, lymph node and leukocytes. Defects in the TBC1D4 gene may cause atopic dermatitis (AD), sometimes referred to as eczema, an atopic chronic skin disease. The skin of affected individuals reacts to irritants or allergens and becomes red, flaky and itchy. The skin is also more vulnerable to inflammations, and symptoms can grow or disappear over time.
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Poids moléculaire
- 147kDa
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ID gène
- 9882
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UniProt
- O60343
Antigène
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