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Caspase 5 p10 anticorps (Cleaved-Ser331)

L’anticorps Lapin Polyclonal anti-Caspase 5 p10 a été validé pour WB et ELISA. Il convient pour détecter Caspase 5 p10 dans des échantillons de Humain.
N° du produit ABIN5955945

Aperçu rapide pour Caspase 5 p10 anticorps (Cleaved-Ser331) (ABIN5955945)

Antigène

Caspase 5 p10

Reactivité

  • 3
  • 1
  • 1
Humain

Hôte

  • 3
Lapin

Clonalité

  • 3
Polyclonal

Conjugué

  • 3
Cet anticorp Caspase 5 p10 est non-conjugé

Application

Western Blotting (WB), ELISA
  • Épitope

    • 2
    • 1
    • 1
    Cleaved-Ser331

    Specificité

    Apoptosis related cysteine protease,CASP-5,CASP5,CASP5,Caspase-5 subunit p10,ICE(rel)-III,ICERELIII,ICH 3,ICH 3 protease,Protease ICH-3,Protease TY,TY,TY protease

    Purification

    Affinity purification

    Immunogène

    Synthesized peptide derived from the C-terminal region of human Caspase-5 p10

    Isotype

    IgG
  • Indications d'application

    WB 1:500-1:2000, ELISA 1:20000

    Restrictions

    For Research Use only
  • Concentration

    1 mg/mL

    Buffer

    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène

    Caspase 5 p10

    Autre désignation

    Caspase-5 p10

    Sujet

    This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein, this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene.

    Poids moléculaire

    48kDa

    ID gène

    838

    UniProt

    P51878
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