KLF1 anticorps (Lys274)

N° du produit ABIN5960969

Cet anticorps Lapin Polyclonal détecte spécifiquement KLF1 dans ELISA et WB. Il présente une réactivité envers Humain.

Aperçu rapide pour KLF1 anticorps (Lys274) (ABIN5960969)

Antigène: KLF1 (Kruppel-Like Factor 1 (erythroid) (KLF1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLF1 est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-KLF1 anticorps

Épitope: Lys274

Specificité: CDAN4,EKLF,EKLF PEN,Erythroid krueppel like transcription factor (EKLF) (Erythroid transcription factor),Erythroid krueppel-like transcription factor,Erythroid Kruppel like factor,Erythroid specific transcription factor EKLF,HBFQTL6,Human erythroid-specific transcription factor EKLF mRNA complete cds,INLU,Klf1,KLF1,Krueppel-like factor 1,Kruppel like factor 1 (erythroid)

Purification: Affinity purification

Immunogène: Synthesized peptide derived from human EKLF around the non-acetylation site of K274.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, ELISA 1:20000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur KLF1

Antigène: KLF1 (Kruppel-Like Factor 1 (erythroid) (KLF1))

Autre désignation: EKLF

Sujet: This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype.KLF1 (Kruppel Like Factor 1) is a Protein Coding gene. Diseases associated with KLF1 include Dyserythropoietic Anemia, Congenital, Type Iv and Hereditary Persistence Of Fetal Hemoglobin-Sickle Cell Disease Syndrome. Among its related pathways are Hematopoietic Stem Cell Differentiation. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is KLF4.

Poids moléculaire: 38kDa

ID gène: 10661

UniProt: Q13351