GABBR1 anticorps

N° du produit ABIN5961044

Cet anticorps Lapin Polyclonal détecte spécifiquement GABBR1 dans WB, ELISA et IHC (p). Il présente une réactivité envers Humain, Rat, Souris et Singe.

Aperçu rapide pour GABBR1 anticorps (ABIN5961044)

Antigène: GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

Reactivité: Humain, Rat, Souris, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GABBR1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-GABBR1 anticorps

Specificité: DJ271M21.1.1,dJ271M21.1.2,FLJ92613,GABA-B receptor 1,GABA-B-R1,GABA-BR1,GABAB R1,GABAB subunit 1c,GABABR1,GABBR1 3,GABBR1,GABR1,Gamma aminobutyric acid (GABA) B receptor 1,Gamma-aminobutyric acid type B receptor subunit 1,Gb1,GPRC3A,Seven transmembrane helix receptor

Purification: Affinity purification

Immunogène: Synthesized peptide derived from the C-terminal region of human GABAB R1

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GABBR1

Antigène: GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

Autre désignation: GABAB R1

Sujet: Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates multiple transcript variants. 

Poids moléculaire: 108kDa

ID gène: 2550

UniProt: Q9UBS5

Pathways: Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process