IL-17 anticorps
Aperçu rapide pour IL-17 anticorps (ABIN604996)
Antigène
Voir toutes IL-17 (IL17) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Marque
- IHC-plus™
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Specificité
- Recognizes mouse Interleukin 17, a 32kD disulfide-linked homodimer consisting of two 136 amino acid chains, which belong to the IL-17 family (classified as IL-17A to IL-17F), and signal through the IL-17 receptor (IL-17R/CDw217). IL-17 is produced primarily by activated CD4+ T cells and induces a variety of target cells to secrete inflammatory cytokines, including IL-1beta, IL-6, TNFalpha, IFNgamma and granulocyte colony-stimulating factor, as well as synergizing with other inflammatory cytokines and agonists. The role of IL-17 in bone metabolism has become a focus area for studies into Rheumatoid Arthritis, in which levels of IL-17 are significantly increased and may contribute to bone destruction.
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Purification
- Purified from ascites.
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Immunogène
- E. coli-expressed, recombinant mouse IL-17A
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Isotype
- IgG1
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Indications d'application
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Approved: ELISA, Flo, IHC, IHC-P (10 μg/mL), WB
Usage: ELISA: This antibody can be used in a sandwich ELISA with LS-C41752 as a detection antibody. -
Commentaires
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Target Species of Antibody: Mouse
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Borate buffered saline.
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Conseil sur la manipulation
- Minimize freezing and thawing.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot and store at -20°C. Avoid freeze-thaw cycles.
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- IL-17 (IL17) (Interleukin 17 (IL17))
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Autre désignation
- IL17 / IL-17
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Sujet
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Name/Gene ID: IL17
Synonyms: IL17
Antigène
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