CD46 anticorps (PE)

N° du produit ABIN610111

Cet anticorps Souris Monoclonal détecte spécifiquement CD46 dans WB, FACS et Func. Il présente une réactivité envers Humain et a été mentionné dans 3+ publications.

Aperçu rapide pour CD46 anticorps (PE) (ABIN610111)

Antigène: CD46

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD46 est conjugé à/à la PE

Application: Western Blotting (WB), Flow Cytometry (FACS), Functional Studies (Func)

Clone: 169-1-EA-3

Détail du produit anti-CD46 anticorps (PE)

Specificité: SCR1 epitope of CD46.

Purification: Gel filtration

Immunogène: Human PBL and EBV transformed LCL.

Isotype: IgG2a

Information d'application

Indications d'application: Approved: Flo, Func, WB

Usage: Function: Does not block MCP function. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 500 mM potassium chloride, 150 mM sodium chloride, 15 % Glycerol, 0.2 % BSA, 0.04 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze. Product is photosensitive and should be protected from light.

Stock: 4 °C

Stockage commentaire: Store at 4°C. Do not freeze. Protect from light.

Références pour anticorps anti-CD46 (PE) (ABIN610111)

Saucier, Papavasiliou, Palazzo, Naujokas, Kremer, Park: "Use of signal specific receptor tyrosine kinase oncoproteins reveals that pathways downstream from Grb2 or Shc are sufficient for cell transformation and metastasis." dans: Oncogene, Vol. 21, Issue 12, pp. 1800-11, (2002) (PubMed).

Elowe, Holland, Kulkarni, Pawson: "Downregulation of the Ras-mitogen-activated protein kinase pathway by the EphB2 receptor tyrosine kinase is required for ephrin-induced neurite retraction." dans: Molecular and cellular biology, Vol. 21, Issue 21, pp. 7429-41, (2001) (PubMed).

Miki, Miura, Matuoka, Nakata, Hirokawa, Orita, Kaibuchi, Takai, Takenawa: "Association of Ash/Grb-2 with dynamin through the Src homology 3 domain." dans: The Journal of biological chemistry, Vol. 269, Issue 8, pp. 5489-92, (1994) (PubMed).

Détails sur CD46

Antigène: CD46

Autre désignation: MCP / CD46

Sujet: Name/Gene ID: CD46

Synonyms: CD46, AHUS2, CD46 antigen, MCP, Measles virus receptor, TLX, MIC10, TRA2.10, Membrane cofactor protein

ID gène: 4179

UniProt: P15529

Pathways: Regulation of Actin Filament Polymerization