CD58 anticorps (Biotin)

N° du produit ABIN610161

Cet anticorps anti-CD58 est un anticorps Souris Monoclonal détectant CD58 dans FACS et Func. Adapté pour Humain. Ce Primary Antibody a été cité dans 3+ publications.

Aperçu rapide pour CD58 anticorps (Biotin) (ABIN610161)

Antigène: CD58

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD58 est conjugé à/à la Biotin

Application: Flow Cytometry (FACS), Functional Studies (Func)

Clone: TS2-9

Détail du produit anti-CD58 anticorps (Biotin)

Specificité: Both transmembrane and GPI anchored CD58.

Purification: Protein A purified

Immunogène: Human cytotoxic T cells.

Isotype: IgG1

Information d'application

Indications d'application: Approved: Flo, Func

Usage: Function: Inhibits HLA-DR mediated T cell cytotoxicity. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride, 5 % Glycerol, 0.2 % BSA, 0.04 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze.

Stock: 4 °C

Stockage commentaire: Store at 4°C. Do not freeze.

Références pour anticorps anti-CD58 (Biotin) (ABIN610161)

Dillon, Creer, Kerr, Kümin, Dickson: "Basolateral targeting of ERBB2 is dependent on a novel bipartite juxtamembrane sorting signal but independent of the C-terminal ERBIN-binding domain." dans: Molecular and cellular biology, Vol. 22, Issue 18, pp. 6553-63, (2002) (PubMed).

Piechocki, Pilon, Wei: "Complementary antitumor immunity induced by plasmid DNA encoding secreted and cytoplasmic human ErbB-2." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 6, pp. 3367-74, (2001) (PubMed).

Xu, Mimnaugh, Rosser, Nicchitta, Marcu, Yarden, Neckers: "Sensitivity of mature Erbb2 to geldanamycin is conferred by its kinase domain and is mediated by the chaperone protein Hsp90." dans: The Journal of biological chemistry, Vol. 276, Issue 5, pp. 3702-8, (2001) (PubMed).

Détails sur CD58

Antigène: CD58

Autre désignation: CD58

Sujet: Name/Gene ID: CD58
Family: Immunoglobulin

Synonyms: CD58, CD58 antigen, AG3, LFA-3, LFA3, Surface glycoprotein LFA-3, Surface glycoprotein lfa3, CD58 Molecule

ID gène: 965

UniProt: P19256