SH3PXD2A anticorps
Aperçu rapide pour SH3PXD2A anticorps (ABIN6135104)
Antigène
Voir toutes SH3PXD2A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Humain, Souris
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- A synthetic peptide of human SH3PXD2A
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- SH3PXD2A (SH3 and PX Domains 2A (SH3PXD2A))
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Autre désignation
- SH3PXD2A
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Sujet
- Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs, NADPH oxidases (NOXs and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.,SH3PXD2A,FISH,SH3MD1,TKS5,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Ubiquitin,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,SH3PXD2A
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Poids moléculaire
- 102 kDa/121 kDa/125 kDa
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ID gène
- 9644
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UniProt
- Q5TCZ1
Antigène
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