RPS6 anticorps (pSer240, pSer244)
Aperçu rapide pour RPS6 anticorps (pSer240, pSer244) (ABIN6136242)
Antigène
Voir toutes RPS6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pSer240, pSer244
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Séquence
- STSKS
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Phosphorylated Antibodies
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Immunogène
- A synthetic phosphorylated peptide around S240 & S244 of human RPS6 (NP_001001.2).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:100
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Commentaires
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- RPS6 (Ribosomal Protein S6 (RPS6))
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Autre désignation
- RPS6
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Sujet
- Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.,RPS6,S6,RPS6,Epigenetics & Nuclear Signaling,RNA Binding,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Signal Transduction,PI3K-Akt Signaling Pathway,MAPK-Erk Signaling Pathway,Akt downstream targets,Protein phosphorylation,RPS6
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Poids moléculaire
- 28 kDa
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ID gène
- 6194
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UniProt
- P62753
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Pathways
- Carbohydrate Homeostasis, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
Antigène
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