ALAS1 anticorps (AA 1-250)

N° du produit ABIN6136754

L’anticorps Lapin Polyclonal anti-ALAS1 a été validé pour WB. Il convient pour détecter ALAS1 dans des échantillons de Humain.

Aperçu rapide pour ALAS1 anticorps (AA 1-250) (ABIN6136754)

Antigène: ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALAS1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ALAS1 anticorps

Épitope: AA 1-250

Séquence: MESVVRRCPF LSRVPQAFLQ KAGKSLLFYA QNCPKMMEVG AKPAPRALST AAVHYQQIKE TPPASEKDKT AKAKVQQTPD GSQQSPDGTQ LPSGHPLPAT SQGTASKCPF LAAQMNQRGS SVFCKASLEL QEDVQEMNAV RKEVAETSAG PSVVSVKTDG GDPSGLLKNF QDIMQKQRPE RVSHLLQDNL PKSVSTFQYD RFFEKKIDEK KNDHTYRVFK TVNRRAHIFP MADDYSDSLI TKKQVSVWCS

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ALAS1 (NP_954635.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ALAS1

Antigène: ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))

Autre désignation: ALAS1

Sujet: This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme, a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms.,ALAS1,ALAS,ALAS-H,ALAS3,ALASH,MIG4,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Cardiovascular,Blood,ALAS1

Poids moléculaire: 12 kDa/70 kDa

ID gène: 211

UniProt: P13196

Pathways: Regulation of Lipid Metabolism by PPARalpha