ANTXR1 anticorps (AA 84-333)

N° du produit ABIN6136913

Cet anticorps anti-ANTXR1 est un anticorps Lapin Polyclonal détectant ANTXR1 dans WB. Adapté pour Humain.

Aperçu rapide pour ANTXR1 anticorps (AA 84-333) (ABIN6136913)

Antigène: ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANTXR1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ANTXR1 anticorps

Épitope: AA 84-333

Séquence: VFSTRGTTLM KLTEDREQIR QGLEELQKVL PGGDTYMHEG FERASEQIYY ENRQGYRTAS VIIALTDGEL HEDLFFYSER EANRSRDLGA IVYCVGVKDF NETQLARIAD SKDHVFPVND GFQALQGIIH SILKKSCIEI LAAEPSTICA GESFQVVVRG NGFRHARNVD RVLCSFKIND SVTLNEKPFS VEDTYLLCPA PILKEVGMKA ALQVSMNDGL SFISSSVIIT TTHCSLHKIA SGPTTAACME

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 84-333 of human ANTXR1 (NP_060623.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ANTXR1

Antigène: ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))

Autre désignation: ANTXR1

Sujet: This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.,ANTXR1,ATR,GAPO,TEM8,Cardiovascular,Angiogenesis,ANTXR1

Poids moléculaire: 33 kDa/37 kDa/39 kDa/41 kDa/59 kDa/62 kDa

ID gène: 84168

UniProt: Q9H6X2