APEH anticorps (AA 1-260)
Aperçu rapide pour APEH anticorps (AA 1-260) (ABIN6136977)
Antigène
Voir toutes APEH AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-260
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Séquence
- MERQVLLSEP EEAAALYRGL SRQPALSAAC LGPEVTTQYG GQYRTVHTEW TQRDLERMEN IRFCRQYLVF HDGDSVVFAG PAGNSVETRG ELLSRESPSG TMKAVLRKAG GTGPGEEKQF LEVWEKNRKL KSFNLSALEK HGPVYEDDCF GCLSWSHSET HLLYVAEKKR PKAESFFQTK ALDVSASDDE IARLKKPDQA IKGDQFVFYE DWGENMVSKS IPVLCVLDVE SGNISVLEGV PENVSPGQAF WAPGDAGVVF
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human APEH (NP_001631.3).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- APEH (N-Acylaminoacyl-Peptide Hydrolase (APEH))
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Autre désignation
- APEH
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Sujet
- This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.,APEH,AARE,ACPH,APH,D3F15S2,D3S48E,DNF15S2,OPH,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Ubiquitin,APEH
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Poids moléculaire
- 81 kDa
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ID gène
- 327
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UniProt
- P13798
Antigène
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