ARHGAP44 anticorps (AA 666-772)

N° du produit ABIN6137082

Cet anticorps anti-ARHGAP44 est un anticorps Lapin Polyclonal détectant ARHGAP44 dans WB. Adapté pour Humain.

Aperçu rapide pour ARHGAP44 anticorps (AA 666-772) (ABIN6137082)

Antigène: ARHGAP44 (rho GTPase Activating Protein 44 (ARHGAP44))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGAP44 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ARHGAP44 anticorps

Épitope: AA 666-772

Séquence: MADQSAGQPS PVSLSPTPPS TPSPYGLSYP QGYSLASGQL SPAAAPPLAS PSVFTSTLSK SRPTPKPRQR PTLPPPQPPT VNLSASSPQS TEAPMLDGMS PGESMST

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 666-772 of human ARHGAP44 (NP_055674.4).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ARHGAP44

Antigène: ARHGAP44 (rho GTPase Activating Protein 44 (ARHGAP44))

Autre désignation: ARHGAP44

Sujet: GTPase-activating protein (GAP that stimulates the GTPase activity of Rho-type GTPases. Thereby, controls Rho-type GTPases cycling between their active GTP-bound and inactive GDP-bound states. Acts as a GAP at least for CDC42 and RAC1. In neurons, is involved in dendritic spine formation and synaptic plasticity in a specific RAC1-GAP activity (By similarity. Limits the initiation of exploratory dendritic filopodia. Recruited to actin-patches that seed filopodia, binds specifically to plasma membrane sections that are deformed inward by acto-myosin mediated contractile forces. Acts through GAP activity on RAC1 to reduce actin polymerization necessary for filopodia formation (By similarity. In association with SHANK3, promotes GRIA1 exocytosis from recycling endosomes and spine morphological changes associated to long-term potentiation (By similarity.,ARHGAP44,NPC-A-10,RICH2,Signal Transduction,G protein signaling,Signal Transduction,ARHGAP44

Poids moléculaire: 83 kDa/88 kDa/89 kDa

ID gène: 9912

UniProt: Q17R89