ASCC2 anticorps (AA 488-757)

N° du produit ABIN6137169

Détail du produit anti-ASCC2 anticorps

Antigène: ASCC2 (Activating Signal Cointegrator 1 Complex Subunit 2 (ASCC2))

Épitope: AA 488-757

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ASCC2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: LACLEYYHYD PEQVINNILE ERLAPTLSQL DRNLDREMKP DPTPLLTSRH NVFQNDEFDV FSRDSVDLSR VHKGKSTRKE ENTRSLLNDK RAVAAQRQRY EQYSVVVEEV PLQPGESLPY HSVYYEDEYD DTYDGNQVGA NDADSDDELI SRRPFTIPQV LRTKVPREGQ EEDDDDEEDD ADEEAPKPDH FVQDPAVLRE KAEARRMAFL AKKGYRHDSS TAVAGSPRGH GQSRETTQER RKKEANKATR ANHNRRTMAD RKRSKGMIPS

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 488-757 of human ASCC2 (NP_115580.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ASCC2

Antigène: ASCC2 (Activating Signal Cointegrator 1 Complex Subunit 2 (ASCC2))

Autre désignation: ASCC2 (ASCC2 Produits)

Synonymes: anticorps MGC63666, anticorps zgc:63666, anticorps ASCC2, anticorps ascc2, anticorps asc1p100, anticorps ASC1p100, anticorps p100, anticorps 1700011I11Rik, anticorps 2610034L15Rik, anticorps AI482016, anticorps AW046480, anticorps RGD1561422, anticorps activating signal cointegrator 1 complex subunit 2, anticorps activating signal cointegrator 1 complex subunit 2 S homeolog, anticorps ascc2, anticorps ASCC2, anticorps MCYG_08331, anticorps ascc2.S, anticorps Ascc2

Sujet: Plays a role in DNA damage repair as component of the ASCC complex. Recruits ASCC3 and ALKBH3 to sites of DNA damage by binding to polyubiquitinated proteins that have 'Lys-63'-linked polyubiquitin chains. Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation. Involved in activation of the ribosome quality control (RQC pathway, a pathway that degrades nascent peptide chains during problematic translation. As part of the ribosome quality control trigger (RQT complex, recognizes ZNF598-dependent ubiquitination of stalled ribosomes (By similarity.,ASCC2,ASC1p100,p100,Signal Transduction,ASCC2

Poids moléculaire: 41 kDa/77 kDa/86 kDa

ID gène: 84164

UniProt: Q9H1I8