ASIP anticorps (AA 23-132)

N° du produit ABIN6137195

Cet anticorps Lapin Polyclonal détecte spécifiquement ASIP dans IF. Il présente une réactivité envers Humain.

Aperçu rapide pour ASIP anticorps (AA 23-132) (ABIN6137195)

Antigène: ASIP (Agouti Signaling Protein (ASIP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ASIP est non-conjugé

Application: Immunofluorescence (IF)

Détail du produit anti-ASIP anticorps

Épitope: AA 23-132

Séquence: HLPPEEKLRD DRSLRSNSSV NLLDVPSVSI VALNKKSKQI GRKAAEKKRS SKKEASMKKV VRPRTPLSAP CVATRNSCKP PAPACCDPCA SCQCRFFRSA CSCRVLSLNC

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 23-132 of human ASIP (NP_001663.2).

Isotype: IgG

Information d'application

Indications d'application: IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ASIP

Antigène: ASIP (Agouti Signaling Protein (ASIP))

Autre désignation: ASIP

Sujet: In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may (1) affect the quality of hair pigmentation, (2) act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, (3) play a role in neuroendocrine aspects of melanocortin action, and (4) have a functional role in regulating lipid metabolism in adipocytes.,ASIP,AGSW,AGTI,AGTIL,ASP,SHEP9,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Neuroscience,ASIP

Poids moléculaire: 14 kDa

ID gène: 434

UniProt: P42127

Pathways: Cell-Cell Junction Organization, Feeding Behaviour