ATG2A anticorps (AA 700-800)
Aperçu rapide pour ATG2A anticorps (AA 700-800) (ABIN6137252)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 700-800
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Séquence
- DLHGIYEDGG KPPVPCLRVS KALDPKSTGR KYFLPQVVVT VNPQSSSTQW EVAPEKGEEL ELSVESPCEL REPEPSPFSS KRTMYETEEM VIPGDPEEMR T
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Réactivité croisée
- Humain
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- A synthetic peptide corresponding to a sequence within amino acids 700-800 of human ATG2A (NP_055919.2).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Commentaires
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- ATG2A (ATG2 Autophagy Related 2 Homolog A (S. Cerevisiae) (ATG2A))
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Autre désignation
- ATG2A
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Sujet
- Lipid transfer protein involved in autophagosome assembly. Tethers the edge of the isolation membrane (IM to the endoplasmic reticulum (ER and mediates direct lipid transfer from ER to IM for IM expansion. Binds to the ER exit site (ERES, which is the membrane source for autophagosome formation, and extracts phospholipids from the membrane source and transfers them to ATG9 (ATG9A or ATG9B to the IM for membrane expansion. Lipid transfer activity is enhanced by WIPI1 and WDR45/WIPI4, which promote ATG2A-association with phosphatidylinositol 3-monophosphate (PI3P-containing membranes. Also regulates lipid droplets morphology and distribution within the cell.,ATG2A,Endocrine & Metabolism,Mitochondrial metabolism,ATG2A
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Poids moléculaire
- 13 kDa/35 kDa/212 kDa/213 kDa
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ID gène
- 23130
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UniProt
- Q2TAZ0
Antigène
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