CBX6 anticorps (AA 80-180)
Aperçu rapide pour CBX6 anticorps (AA 80-180) (ABIN6138026)
Antigène
Voir toutes CBX6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 80-180
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Séquence
- LLKARAQAEA LRISDVHFSV KPSASASSPK LHSSAAVHRL KKDIRRCHRM SRRPLPRPDP QGGSPGLRPP ISPFSETVRI INRKVKPREP KRNRIILNLK V
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 80-180 of human CBX6 (NP_055107.3).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- CBX6 (Chromobox Homolog 6 (CBX6))
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Autre désignation
- CBX6
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Sujet
- Component of a Polycomb group (PcG multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Possibly contributes to the target selectivity of the PRC1 complex by binding specific regions of chromatin. Recruitment to chromatin might occur in an H3K27me3-independent fashion (By similarity. May have a PRC1-independent function in embryonic stem cells (By similarity.,CBX6,Epigenetics & Nuclear Signaling,Chromatin Remodeling,CBX6
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Poids moléculaire
- 43 kDa
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ID gène
- 23466
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UniProt
- O95503
Antigène
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