CMA1 anticorps (AA 81-247)
Aperçu rapide pour CMA1 anticorps (AA 81-247) (ABIN6138762)
Antigène
Voir toutes CMA1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 81-247
-
Séquence
- ITEEEDTWQK LEVIKQFRHP KYNTSTLHHD IMLLKLKEKA SLTLAVGTLP FPSQFNFVPP GRMCRVAGWG RTGVLKPGSD TLQEVKLRLM DPQACSHFRD FDHNLQLCVG NPRKTKSAFK GDSGGPLLCA GVAQGIVSYG RSDAKPPAVF TRISHYRPWI NQILQAN
-
Réactivité croisée
- Humain, Souris
-
Attributs du produit
- Polyclonal Antibodies
-
Purification
- Affinity purification
-
Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 81-247 of human Mast Cell Chymase (Mast Cell Chymase (CMA1)) (NP_001827.1).
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB,1:500 - 1:2000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- CMA1 (Chymase 1, Mast Cell (CMA1))
-
Autre désignation
- CMA1
-
Sujet
- This gene encodes a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Alternative splicing results in multiple variants.,CMA1,CYH,MCT1,chymase,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,Cardiovascular,Blood,CMA1
-
Poids moléculaire
- 14 kDa/27 kDa
-
ID gène
- 1215
-
UniProt
- P23946
-
Pathways
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis
Antigène
-