CNOT8 anticorps (AA 1-292)

N° du produit ABIN6138786

Cet anticorps Lapin Polyclonal détecte spécifiquement CNOT8 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour CNOT8 anticorps (AA 1-292) (ABIN6138786)

Antigène: CNOT8 (CCR4-NOT Transcription Complex, Subunit 8 (CNOT8))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CNOT8 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CNOT8 anticorps

Épitope: AA 1-292

Séquence: MPAALVENSQ VICEVWASNL EEEMRKIREI VLSYSYIAMD TEFPGVVVRP IGEFRSSIDY QYQLLRCNVD LLKIIQLGLT FTNEKGEYPS GINTWQFNFK FNLTEDMYSQ DSIDLLANSG LQFQKHEEEG IDTLHFAELL MTSGVVLCDN VKWLSFHSGY DFGYMVKLLT DSRLPEEEHE FFHILNLFFP SIYDVKYLMK SCKNLKGGLQ EVADQLDLQR IGRQHQAGSD SLLTGMAFFR MKELFFEDSI DDAKYCGRLY GLGTGVAQKQ NEDVDSAQEK MSILAIINNM QQ

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-292 of human CNOT8 (NP_004770.4).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CNOT8

Antigène: CNOT8 (CCR4-NOT Transcription Complex, Subunit 8 (CNOT8))

Autre désignation: CNOT8

Sujet: Has 3'-5' poly(A exoribonuclease activity for synthetic poly(A RNA substrate. Its function seems to be partially redundant with that of CNOT7. Catalytic component of the CCR4-NOT complex which is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity.,CNOT8,CAF1,CALIF,Caf1b,POP2,hCAF1,Epigenetics & Nuclear Signaling,Transcription Factors,CNOT8

Poids moléculaire: 21 kDa/27 kDa/33 kDa

ID gène: 9337

UniProt: Q9UFF9