COMP anticorps (AA 20-160)

N° du produit ABIN6138864

Cet anticorps Lapin Polyclonal détecte spécifiquement COMP dans WB et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour COMP anticorps (AA 20-160) (ABIN6138864)

Antigène: COMP (Cartilage Oligomeric Matrix Protein (COMP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COMP est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-COMP anticorps

Épitope: AA 20-160

Séquence: GQGQSPLGSD LGPQMLRELQ ETNAALQDVR ELLRQQVREI TFLKNTVMEC DACGMQQSVR TGLPSVRPLL HCAPGFCFPG VACIQTESGA RCGPCPAGFT GNGSHCTDVN ECNAHPCFPR VRCINTSPGF RCEACPPGYS G

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 20-160 of human COMP (NP_000086.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:10 - 1:100

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur COMP

Antigène: COMP (Cartilage Oligomeric Matrix Protein (COMP))

Autre désignation: COMP

Sujet: The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Contraction or expansion of a 5 aa aspartate repeat and other mutations can cause pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).,COMP,EDM1,EPD1,MED,PSACH,THBS5,TSP5,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,Cytoskeleton,Extracellular Matrix,Bone,Stem Cells,Mesenchymal Stem Cells,COMP

Poids moléculaire: 77 kDa/82 kDa

ID gène: 1311

UniProt: P49747