COPG anticorps (AA 555-874)
Aperçu rapide pour COPG anticorps (AA 555-874) (ABIN6138875)
Antigène
Voir toutes COPG AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 555-874
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Séquence
- IPGLERALQQ YTLEPSEKPF DLKSVPLATA PMAEQRTEST PITAVKQPEK VAATRQEIFQ EQLAAVPEFR GLGPLFKSSP EPVALTESET EYVIRCTKHT FTNHMVFQFD CTNTLNDQTL ENVTVQMEPT EAYEVLCYVP ARSLPYNQPG TCYTLVALPK EDPTAVACTF SCMMKFTVKD CDPTTGETDD EGYEDEYVLE DLEVTVADHI QKVMKLNFEA AWDEVGDEFE KEETFTLSTI KTLEEAVGNI VKFLGMHPCE RSDKVPDNKN THTLLLAGVF RGGHDILVRS RLLLLDTVTM QVTARSLEEL PVDIILASVG
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 555-874 of human COPG1 (NP_057212.1).
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Isotype
- IgG
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Indications d'application
- WB,1:1000 - 1:2000,IHC,1:50 - 1:200
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Commentaires
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- COPG (Coatomer Protein Complex, Subunit gamma (COPG))
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Autre désignation
- COPG1
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Sujet
- The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs, which are small GTP-binding proteins, the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors. Required for limiting lipid storage in lipid droplets. Involved in lipid homeostasis by regulating the presence of perilipin family members PLIN2 and PLIN3 at the lipid droplet surface and promoting the association of adipocyte triglyceride lipase (PNPLA2 with the lipid droplet surface to mediate lipolysis (By similarity.,COPG1,COPG,Signal Transduction,COPG1
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Poids moléculaire
- 97 kDa
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ID gène
- 22820
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UniProt
- Q9Y678
Antigène
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