Cathepsin F anticorps (AA 270-484)

N° du produit ABIN6139225

Cet anticorps anti-Cathepsin F Polyclonal Lapin (ABIN6139225) détecte spécifiquement Cathepsin F dans WB, IHC et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Cathepsin F anticorps (AA 270-484) (ABIN6139225)

Antigène: Cathepsin F (CTSF)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cathepsin F est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-Cathepsin F anticorps

Épitope: AA 270-484

Séquence: LAPPEWDWRS KGAVTKVKDQ GMCGSCWAFS VTGNVEGQWF LNQGTLLSLS EQELLDCDKM DKACMGGLPS NAYSAIKNLG GLETEDDYSY QGHMQSCNFS AEKAKVYIND SVELSQNEQK LAAWLAKRGP ISVAINAFGM QFYRHGISRP LRPLCSPWLI DHAVLLVGYG NRSDVPFWAI KNSWGTDWGE KGYYYLHRGS GACGVNTMAS SAVVD

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 270-484 of human CTSF (NP_003784.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Cathepsin F

Antigène: Cathepsin F (CTSF)

Autre désignation: CTSF

Sujet: Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. Cathepsins generally contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF encodes a predicted protein of 484 amino acids which contains a 19 residue signal peptide. Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway. The cathepsin F gene is ubiquitously expressed, and it maps to chromosome 11q13, close to the gene encoding cathepsin W.,CTSF,CATSF,CLN13,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,CTSF

Poids moléculaire: 53 kDa

ID gène: 8722

UniProt: Q9UBX1