CXCR3 anticorps (AA 289-368)
Aperçu rapide pour CXCR3 anticorps (AA 289-368) (ABIN6139279)
Antigène
Voir toutes CXCR3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 289-368
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Séquence
- NCGRESRVDV AKSVTSGLGY MHCCLNPLLY AFVGVKFRER MWMLLLRLGC PNQRGLQRQP SSSRRDSSWS ETSEASYSGL
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Réactivité croisée
- Humain, Souris
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 289-368 of human CXCR3 (NP_001495.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))
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Autre désignation
- CXCR3
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Sujet
- This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716).,CXCR3,CD182,CD183,CKR-L2,CMKAR3,GPR9,IP10-R,Mig-R,MigR,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Immunology & Inflammation,CD markers,Cell Intrinsic Innate Immunity Signaling Pathway,Chemokines,Chemokine,Neuroscience,Calcium Signaling,Cardiovascular,CXCR3
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Poids moléculaire
- 28 kDa/40 kDa/45 kDa
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ID gène
- 2833
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UniProt
- P49682
Antigène
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