DDX39B anticorps (AA 319-428)

N° du produit ABIN6139492

Cet anticorps Lapin Polyclonal détecte spécifiquement DDX39B dans IHC, WB et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour DDX39B anticorps (AA 319-428) (ABIN6139492)

Antigène: DDX39B (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39B (DDX39B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DDX39B est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-DDX39B anticorps

Épitope: AA 319-428

Séquence: RGMPQEERLS RYQQFKDFQR RILVATNLFG RGMDIERVNI AFNYDMPEDS DTYLHRVARA GRFGTKGLAI TFVSDENDAK ILNDVQDRFE VNISELPDEI DISSYIEQTR

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 319-428 of human UAP56/UAP56/DDX39B (NP_004631.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur DDX39B

Antigène: DDX39B (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39B (DDX39B))

Autre désignation: DDX39B

Sujet: This gene encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing. The encoded protein is an essential splicing factor required for association of U2 small nuclear ribonucleoprotein with pre-mRNA, and it also plays an important role in mRNA export from the nucleus to the cytoplasm. This gene belongs to a cluster of genes localized in the vicinity of the genes encoding tumor necrosis factor alpha and tumor necrosis factor beta. These genes are all within the human major histocompatibility complex class III region. Mutations in this gene may be associated with rheumatoid arthritis. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on both chromosomes 6 and 11. Read-through transcription also occurs between this gene and the upstream ATP6V1G2 (ATPase, H+ transporting, lysosomal 13 kDa, V1 subunit G2) gene.,DDX39B,BAT1,D6S81E,UAP56,Epigenetics & Nuclear Signaling,DDX39B

Poids moléculaire: 48 kDa/50 kDa

ID gène: 7919

UniProt: Q13838

Pathways: Ribonucleoprotein Complex Subunit Organization