Deoxyguanosine Kinase anticorps (AA 40-277)
Aperçu rapide pour Deoxyguanosine Kinase anticorps (AA 40-277) (ABIN6139574)
Antigène
Voir toutes Deoxyguanosine Kinase (DGUOK) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 40-277
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Séquence
- RLSIEGNIAV GKSTFVKLLT KTYPEWHVAT EPVATWQNIQ AAGTQKACTA QSLGNLLDMM YREPARWSYT FQTFSFLSRL KVQLEPFPEK LLQARKPVQI FERSVYSDRY IFAKNLFENG SLSDIEWHIY QDWHSFLLWE FASRITLHGF IYLQASPQVC LKRLYQRARE EEKGIELAYL EQLHGQHEAW LIHKTTKLHF EALMNIPVLV LDVNDDFSEE VTKQEDLMRE VNTFVKNL
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 40-277 of human DGUOK (NP_550438.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Commentaires
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Deoxyguanosine Kinase (DGUOK)
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Autre désignation
- DGUOK
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Sujet
- In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene.,DGUOK,MTDPS3,NCPH,PEOB4,dGK,Signal Transduction,Kinase,DGUOK
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Poids moléculaire
- 9 kDa/17 kDa/21 kDa/27 kDa/29 kDa/32 kDa
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ID gène
- 1716
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UniProt
- Q16854
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Pathways
- Ribonucleoside Biosynthetic Process
Antigène
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