DOK5 anticorps (AA 237-306)
Aperçu rapide pour DOK5 anticorps (AA 237-306) (ABIN6139769)
Antigène
Voir toutes DOK5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 237-306
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Séquence
- LLQSVKNSML QMKMSERAAS LSTMVPLPRS AYWQHITRQH STGQLYRLQD VSSPLKLHRT ETFPAYRSEH
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Réactivité croisée
- Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 237-306 of human DOK5 (NP_060901.2).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- DOK5 (Docking Protein 5 (DOK5))
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Autre désignation
- DOK5
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Sujet
- The protein encoded by this gene is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. Unlike other DOK family proteins, this protein does not interact with RASGAP. This protein is up-regulated in patients with systemic sclerosis and is associated with fibrosis induced by insulin-like growth factor binding protein 5. Alternative splicing of this gene results in multiple transcript variants.,DOK5,C20orf180,IRS-6,IRS6,Signal Transduction,Kinase,Tyrosine kinases,DOK5
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Poids moléculaire
- 22 kDa/35 kDa
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ID gène
- 55816
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UniProt
- Q9P104
Antigène
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