DUSP5 anticorps (AA 315-384)
Aperçu rapide pour DUSP5 anticorps (AA 315-384) (ABIN6139875)
Antigène
Voir toutes DUSP5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 315-384
-
Séquence
- SEILPSTPNP QPPSCQGEAA GSSLIGHLQT LSPDMQGAYC TFPASVLAPV PTHSTVSELS RSPVATATSC
-
Réactivité croisée
- Humain
-
Attributs du produit
- Polyclonal Antibodies
-
Purification
- Affinity purification
-
Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 315-384 of human DUSP5 (NP_004410.3).
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB,1:500 - 1:2000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- DUSP5 (Dual Specificity Phosphatase 5 (DUSP5))
-
Autre désignation
- DUSP5
-
Sujet
- The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus.,DUSP5,DUSP,HVH3,Signal Transduction,DUSP5
-
Poids moléculaire
- 42 kDa
-
ID gène
- 1847
-
UniProt
- Q16690
Antigène
-