EIF3C anticorps (AA 694-913)

N° du produit ABIN6140055

L’anticorps Lapin Polyclonal anti-EIF3C a été validé pour WB, IHC et IF. Il convient pour détecter EIF3C dans des échantillons de Humain.

Aperçu rapide pour EIF3C anticorps (AA 694-913) (ABIN6140055)

Antigène: EIF3C (Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF3C est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-EIF3C anticorps

Épitope: AA 694-913

Séquence: EIPYMAAHES DARRRMISKQ FHHQLRVGER QPLLGPPESM REHVVAASKA MKMGDWKTCH SFIINEKMNG KVWDLFPEAD KVRTMLVRKI QEESLRTYLF TYSSVYDSIS METLSDMFEL DLPTVHSIIS KMIINEELMA SLDQPTQTVV MHRTEPTAQQ NLALQLAEKL GSLVENNERV FDHKQGTYGG YFRDQKDGYR KNEGYMRRGG YRQQQSQTAY

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 694-913 of human EIF3C (NP_003743.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur EIF3C

Antigène: EIF3C (Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C))

Autre désignation: EIF3C

Sujet: Component of the eukaryotic translation initiation factor 3 (eIF-3 complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC. The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.,EIF3C,EIF3CL,EIF3S8,eIF3-p110,Epigenetics & Nuclear Signaling,RNA Binding,Translation Control,EIF3C

Poids moléculaire: 104 kDa/105 kDa

ID gène: 8663

UniProt: Q99613

Pathways: Ribonucleoprotein Complex Subunit Organization