EP400 anticorps (AA 90-330)

N° du produit ABIN6140195

L’anticorps Lapin Polyclonal anti-EP400 a été validé pour WB. Il convient pour détecter EP400 dans des échantillons de Humain.

Aperçu rapide pour EP400 anticorps (AA 90-330) (ABIN6140195)

Antigène: EP400 (E1A Binding Protein P400 (EP400))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EP400 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-EP400 anticorps

Épitope: AA 90-330

Séquence: TLAPLPLPSP TSPGFQFSAQ PRRFEHGSPS YIQVTSPLSQ QVQTQSPTQP SPGPGQALQN VRAGAPGPGL GLCSSSPTGG FVDASVLVRQ ISLSPSSGGH FVFQDGSGLT QIAQGAQVQL QHPGTPITVR ERRPSQPHTQ SGGTIHHLGP QSPAAAGGAG LQPLASPSHI TTANLPPQIS SIIQGQLVQQ QQVLQGPPLP RPLGFERTPG VLLPGAGGAA GFGMTSPPPP TSPSRTAVPP G

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 90-330 of human EP400 (NP_056224.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:1000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur EP400

Antigène: EP400 (E1A Binding Protein P400 (EP400))

Autre désignation: EP400

Sujet: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. May be required for transcriptional activation of E2F1 and MYC target genes during cellular proliferation. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. May regulate ZNF42 transcription activity. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AZ1 from the nucleosome.,EP400,CAGH32,P400,TNRC12,Epigenetics & Nuclear Signaling,Chromatin Remodeling,EP400

Poids moléculaire: 331 kDa/335 kDa/339 kDa/343 kDa

ID gène: 57634

UniProt: Q96L91

Pathways: Chromatin Binding