GCDH anticorps (AA 149-438)

N° du produit ABIN6141009

L’anticorps Lapin Polyclonal anti-GCDH a été validé pour WB. Il convient pour détecter GCDH dans des échantillons de Humain.

Aperçu rapide pour GCDH anticorps (AA 149-438) (ABIN6141009)

Antigène: GCDH (Glutaryl-CoA Dehydrogenase (GCDH))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GCDH est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GCDH anticorps

Épitope: AA 149-438

Séquence: MHPIYAYGSE EQRQKYLPQL AKGELLGCFG LTEPNSGSDP SSMETRAHYN SSNKSYTLNG TKTWITNSPM ADLFVVWARC EDGCIRGFLL EKGMRGLSAP RIQGKFSLRA SATGMIIMDG VEVPEENVLP GASSLGGPFG CLNNARYGIA WGVLGASEFC LHTARQYALD RMQFGVPLAR NQLIQKKLAD MLTEITLGLH ACLQLGRLKD QDKAAPEMVS LLKRNNCGKA LDIARQARDM LGGNGISDEY HVIRHAMNLE AVNTYEGTHD IHALILGRAI TGIQAFTASK

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 149-438 of human GCDH (NP_000150.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:200 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GCDH

Antigène: GCDH (Glutaryl-CoA Dehydrogenase (GCDH))

Autre désignation: GCDH

Sujet: The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Mutations in this gene result in the metabolic disorder glutaric aciduria type 1, which is also known as glutaric acidemia type I. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 12.,GCDH,ACAD5,GCD,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Amino acid metabolism,GCDH

Poids moléculaire: 47 kDa/48 kDa

ID gène: 2639

UniProt: Q92947