GCSH anticorps (AA 1-173)

N° du produit ABIN6141032

Cet anticorps Lapin Polyclonal détecte spécifiquement GCSH dans WB et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour GCSH anticorps (AA 1-173) (ABIN6141032)

Antigène: GCSH (Glycine Cleavage System H Protein (GCSH))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GCSH est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-GCSH anticorps

Épitope: AA 1-173

Séquence: MALRVVRSVR ALLCTLRAVP SPAAPCPPRP WQLGVGAVRT LRTGPALLSV RKFTEKHEWV TTENGIGTVG ISNFAQEALG DVVYCSLPEV GTKLNKQDEF GALESVKAAS ELYSPLSGEV TEINEALAEN PGLVNKSCYE DGWLIKMTLS NPSELDELMS EEAYEKYIKS IEE

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-173 of human GCSH (NP_004474.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GCSH

Antigène: GCSH (Glycine Cleavage System H Protein (GCSH))

Autre désignation: GCSH

Sujet: Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for this gene. Also, several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome.,GCSH,GCE,NKH,Cancer,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,GCSH

Poids moléculaire: 18 kDa

ID gène: 2653

UniProt: P23434