GLE1 anticorps (AA 1-300)

N° du produit ABIN6141121

Cet anticorps anti-GLE1 est un anticorps Lapin Polyclonal détectant GLE1 dans WB. Adapté pour Humain.

Aperçu rapide pour GLE1 anticorps (AA 1-300) (ABIN6141121)

Antigène: GLE1 (GLE1 RNA Export Mediator (GLE1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLE1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GLE1 anticorps

Épitope: AA 1-300

Séquence: MPSEGRCWET LKALRSSDKG RLCYYRDWLL RREDVLEECM SLPKLSSYSG WVVEHVLPHM QENQPLSETS PSSTSASALD QPSFVPKSPD ASSAFSPASP ATPNGTKGKD ESQHTESMVL QSSRGIKVEG CVRMYELVHR MKGTEGLRLW QEEQERKVQA LSEMASEQLK RFDEWKELKQ HKEFQDLREV MEKSSREALG HQEKLKAEHR HRAKILNLKL REAEQQRVKQ AEQERLRKEE GQIRLRALYA LQEEMLQLSQ QLDASEQHKA LLKVDLAAFQ TRGNQLCSLI SGIIRASSES

Réactivité croisée: Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GLE1 (NP_001003722.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:1000 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GLE1

Antigène: GLE1 (GLE1 RNA Export Mediator (GLE1))

Autre désignation: GLE1

Sujet: This gene encodes a predicted 75- kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.,GLE1,GLE1L,LCCS,LCCS1,hGLE1,Epigenetics & Nuclear Signaling,Signal Transduction,GLE1

Poids moléculaire: 75 kDa/79 kDa

ID gène: 2733

UniProt: Q53GS7