Glutaredoxin 1 anticorps (AA 1-106)

N° du produit ABIN6141147

Cet anticorps Lapin Polyclonal détecte spécifiquement Glutaredoxin 1 dans WB, IHC et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour Glutaredoxin 1 anticorps (AA 1-106) (ABIN6141147)

Antigène: Glutaredoxin 1 (GRX1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glutaredoxin 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-Glutaredoxin 1 anticorps

Épitope: AA 1-106

Séquence: MAQEFVNCKI QPGKVVVFIK PTCPYCRRAQ EILSQLPIKQ GLLEFVDITA TNHTNEIQDY LQQLTGARTV PRVFIGKDCI GGCSDLVSLQ QSGELLTRLK QIGALQ

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-106 of human GLRX (NP_001112362.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Glutaredoxin 1

Antigène: Glutaredoxin 1 (GRX1)

Autre désignation: GLRX

Sujet: This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.,GLRX,GRX,GRX1,Cell Biology & Developmental Biology,Endocrine & Metabolism,GLRX

Poids moléculaire: 11 kDa

ID gène: 2745

UniProt: P35754

Pathways: Cell RedoxHomeostasis