GLYR1 anticorps (AA 70-270)

N° du produit ABIN6141170

Cet anticorps anti-GLYR1 Polyclonal Lapin (ABIN6141170) détecte spécifiquement GLYR1 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour GLYR1 anticorps (AA 70-270) (ABIN6141170)

Antigène: GLYR1 (Glyoxylate Reductase 1 Homolog (GLYR1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLYR1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-GLYR1 anticorps

Épitope: AA 70-270

Séquence: MIKINKGKRF QQAVDAVEEF LRRAKGKDQT SSHNSSDDKN RRNSSEERSR PNSGDEKRKL SLSEGKVKKN MGEGKKRVSS GSSERGSKSP LKRAQEQSPR KRGRPPKDEK DLTIPESSTV KGMMAGPMAA FKWQPTASEP VKDADPHFHH FLLSQTEKPA VCYQAITKKL KICEEETGST SIQAADSTAV NGSITPTDKK I

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 70-270 of human GLYR1 (NP_115958.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:100 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GLYR1

Antigène: GLYR1 (Glyoxylate Reductase 1 Homolog (GLYR1))

Autre désignation: GLYR1

Sujet: Nucleosome-destabilizing factor that is recruited to genes during transcriptional activation. Facilitates Pol II transcription through nucleosomes. Binds DNA (in vitro. Recognizes and binds trimethylated 'Lys-36' of histone H3 (H3K36me3. Promotes KDM1B demethylase activity. Stimulates the acetylation of 'Lys-56' of nucleosomal histone H3 (H3K56ac by EP300. Regulates p38 MAP kinase activity by mediating stress activation of p38alpha/MAPK14 and specifically regulating MAPK14 signaling. Indirectly promotes phosphorylation of MAPK14 and activation of ATF2. The phosphorylation of MAPK14 requires upstream activity of MAP2K4 and MAP2K6. Putative oxidoreductase.,GLYR1,BM045,HIBDL,N-PAC,NP60,Epigenetics & Nuclear Signaling,Signal Transduction,Kinase,GLYR1

Poids moléculaire: 51 kDa/52 kDa/58 kDa/59 kDa/60 kDa

ID gène: 84656

UniProt: Q49A26