Granulin anticorps (AA 281-336)

N° du produit ABIN6141429

Cet anticorps anti-Granulin est un anticorps Lapin Polyclonal détectant Granulin dans WB et IF. Adapté pour Humain.

Aperçu rapide pour Granulin anticorps (AA 281-336) (ABIN6141429)

Antigène: Granulin (GRN)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Granulin est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-Granulin anticorps

Épitope: AA 281-336

Séquence: DVKCDMEVSC PDGYTCCRLQ SGAWGCCPFT QAVCCEDHIH CCPAGFTCDT QKGTCE

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 281-336 of human Granulin (NP_002078.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Granulin

Antigène: Granulin (GRN)

Autre désignation: GRN

Sujet: Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis.,GRN,CLN11,GEP,GP88,PCDGF,PEPI,PGRN,granulins,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Immunology & Inflammation,Cytokines,Neuroscience,Neurodegenerative Diseases,GRN

Poids moléculaire: 44 kDa/46 kDa/63 kDa

ID gène: 2896

UniProt: P28799