GSTM2 anticorps (AA 1-218)

N° du produit ABIN6141468

Cet anticorps anti-GSTM2 Polyclonal Lapin (ABIN6141468) détecte spécifiquement GSTM2 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour GSTM2 anticorps (AA 1-218) (ABIN6141468)

Antigène: GSTM2 (Glutathione S-Transferase mu 2 (Muscle) (GSTM2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSTM2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GSTM2 anticorps

Épitope: AA 1-218

Séquence: MPMTLGYWNI RGLAHSIRLL LEYTDSSYEE KKYTMGDAPD YDRSQWLNEK FKLGLDFPNL PYLIDGTHKI TQSNAILRYI ARKHNLCGES EKEQIREDIL ENQFMDSRMQ LAKLCYDPDF EKLKPEYLQA LPEMLKLYSQ FLGKQPWFLG DKITFVDFIA YDVLERNQVF EPSCLDAFPN LKDFISRFEG LEKISAYMKS SRFLPRPVFT KMAVWGNK

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-218 of human GSTM2 (NP_000839.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GSTM2

Antigène: GSTM2 (Glutathione S-Transferase mu 2 (Muscle) (GSTM2))

Autre désignation: GSTM2

Sujet: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.,GSTM2,GST4,GSTM,GSTM2-2,GTHMUS,Signal Transduction,Endocrine & Metabolism,Drug metabolism,GSTM2

Poids moléculaire: 22 kDa/25 kDa

ID gène: 2946

UniProt: P28161

Pathways: Negative Regulation of Transporter Activity