HNRNPA1 anticorps (AA 1-372)

N° du produit ABIN6141896

Détail du produit anti-HNRNPA1 anticorps

Antigène: HNRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1))

Épitope: AA 1-372

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HNRNPA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: MSKSESPKEP EQLRKLFIGG LSFETTDESL RSHFEQWGTL TDCVVMRDPN TKRSRGFGFV TYATVEEVDA AMNARPHKVD GRVVEPKRAV SREDSQRPGA HLTVKKIFVG GIKEDTEEHH LRDYFEQYGK IEVIEIMTDR GSGKKRGFAF VTFDDHDSVD KIVIQKYHTV NGHNCEVRKA LSKQEMASAS SSQRGRSGSG NFGGGRGGGF GGNDNFGRGG NFSGRGGFGG SRGGGGYGGS GDGYNGFGND GGYGGGGPGY SGGSRGYGSG GQGYGNQGSG YGGSGSYDSY NNGGGGGFGG GSGSNFGGGG SYNDFGNYNN QSSNFGPMKG GNFGGRSSGP YGGGGQYFAK PRNQGGYGGS SSSSSYGSGR RF

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-372 of human hnRNP A1 (NP_112420.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-HNRNPA1 (ABIN6141896)

Wei, Dai, Zhou, He, Yao, Zhao, Guo, Yang: "Oroxylin A activates PKM1/HNF4 alpha to induce hepatoma differentiation and block cancer progression." dans: Cell death & disease, Vol. 8, Issue 7, pp. e2944, (2018) (PubMed).

Wang, Fu, Chen, Wu, Fan, Li, Zhu, Jia, Ji, Wang, Wong, Hu, Hui: "SPSB1-mediated HnRNP A1 ubiquitylation regulates alternative splicing and cell migration in EGF signaling." dans: Cell research, Vol. 27, Issue 4, pp. 540-558, (2017) (PubMed).

Détails sur HNRNPA1

Antigène: HNRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1))

Autre désignation: HNRNPA1 (HNRNPA1 Produits)

Synonymes: anticorps HNRPA1, anticorps HNRPA1L3, anticorps hnRNP A1, anticorps hnRNP-A1, anticorps hnrpa1, anticorps TPT1P, anticorps HNRNPA1, anticorps D15Ertd119e, anticorps Hdp, anticorps Hnrpa1, anticorps hnrnp-A1, anticorps ROA1, anticorps zgc:66127, anticorps heterogeneous nuclear ribonucleoprotein A1, anticorps heterogeneous nuclear ribonucleoprotein A1b, anticorps Heterogeneous nuclear ribonucleoprotein A1, anticorps heterogeneous nuclear ribonucleoprotein A1 S homeolog, anticorps ribonucleoprotein A1a, anticorps heterogeneous nuclear ribonucleoprotein A1-like, anticorps heterogeneous nuclear ribonucleoprotein A1a, anticorps HNRNPA1, anticorps hnrnpa1b, anticorps LOC100101226, anticorps roa1, anticorps Hnrnpa1, anticorps hnrnpa1.S, anticorps hnrnpa1, anticorps LOC100359118, anticorps hnrnpa1a

Sujet: This gene encodes a member of a family of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs), which are RNA-binding proteins that associate with pre-mRNAs in the nucleus and influence pre-mRNA processing, as well as other aspects of mRNA metabolism and transport. The protein encoded by this gene is one of the most abundant core proteins of hnRNP complexes and plays a key role in the regulation of alternative splicing. Mutations in this gene have been observed in individuals with amyotrophic lateral sclerosis 20. Multiple alternatively spliced transcript variants have been found. There are numerous pseudogenes of this gene distributed throughout the genome.,HNRNPA1,ALS19,ALS20,HNRPA1,HNRPA1L3,IBMPFD3,UP 1,hnRNP A1,hnRNP-A1,Epigenetics & Nuclear Signaling,RNA Binding,HNRNPA1

Poids moléculaire: 29 kDa/34 kDa/38 kDa

ID gène: 3178

UniProt: P09651