IFIT2 anticorps (AA 273-472)

N° du produit ABIN6142178

L’anticorps anti-IFIT2 Polyclonal Lapin est utilisé pour la détection de IFIT2 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour IFIT2 anticorps (AA 273-472) (ABIN6142178)

Antigène: IFIT2 (Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IFIT2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IFIT2 anticorps

Épitope: AA 273-472

Séquence: ALEYIPNNAY LHCQIGCCYR AKVFQVMNLR ENGMYGKRKL LELIGHAVAH LKKADEANDN LFRVCSILAS LHALADQYED AEYYFQKEFS KELTPVAKQL LHLRYGNFQL YQMKCEDKAI HHFIEGVKIN QKSREKEKMK DKLQKIAKMR LSKNGADSEA LHVLAFLQEL NEKMQQADED SERGLESGSL IPSASSWNGE

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 273-472 of human IFIT2 (NP_001538.4).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur IFIT2

Antigène: IFIT2 (Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2))

Autre désignation: IFIT2

Sujet: IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2'-O-methylation of the 5' cap. The ribose 2'-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation (cap snatching mechanism. Binds AU-rich viral RNAs, with or without 5' triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis.,IFIT2,G10P2,GARG-39,IFI-54,IFI-54K,IFI54,IFIT-2,ISG-54 K,ISG-54K,ISG54,P54,cig42,Epigenetics & Nuclear Signaling,RNA Binding,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microtubules,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,IFIT2

Poids moléculaire: 54 kDa

ID gène: 3433

UniProt: P09913