ILF2 anticorps (AA 1-280)

N° du produit ABIN6142415

Cet anticorps Lapin Polyclonal détecte spécifiquement ILF2 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour ILF2 anticorps (AA 1-280) (ABIN6142415)

Antigène: ILF2 (Interleukin Enhancer Binding Factor 2, 45kDa (ILF2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ILF2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ILF2 anticorps

Épitope: AA 1-280

Séquence: MRGDRGRGRG GRFGSRGGPG GGFRPFVPHI PFDFYLCEMA FPRVKPAPDE TSFSEALLKR NQDLAPNSAE QASILSLVTK INNVIDNLIV APGTFEVQIE EVRQVGSYKK GTMTTGHNVA DLVVILKILP TLEAVAALGN KVVESLRAQD PSEVLTMLTN ETGFEISSSD ATVKILITTV PPNLRKLDPE LHLDIKVLQS ALAAIRHARW FEENASQSTV KVLIRLLKDL RIRFPGFEPL TPWILDLLGH YAVMNNPTRQ PLALNVAYRR CLQILAAGLF

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ILF2 (NP_004506.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ILF2

Antigène: ILF2 (Interleukin Enhancer Binding Factor 2, 45kDa (ILF2))

Autre désignation: ILF2

Sujet: The protein encoded by this gene is a transcription factor required for T-cell expression of the interleukin 2 gene. It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. The encoded 45 kDa protein (NF45, ILF2) forms a complex with the 90 kDa interleukin enhancer-binding factor 3 (NF90, ILF3), and this complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm, to repair DNA breaks by nonhomologous end joining, and to negatively regulate the microRNA processing pathway. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. Alternative splicing results in multiple transcript variants. Related pseudogenes have been found on chromosomes 3 and 14.,ILF2,NF45,PRO3063,Epigenetics & Nuclear Signaling,Transcription Factors,RNA Binding,ILF2

Poids moléculaire: 43 kDa

ID gène: 3608

UniProt: Q12905