ING3 anticorps (AA 1-92)

N° du produit ABIN6142450

Cet anticorps anti-ING3 est un anticorps Lapin Polyclonal détectant ING3 dans WB. Adapté pour Humain.

Aperçu rapide pour ING3 anticorps (AA 1-92) (ABIN6142450)

Antigène: ING3 (Inhibitor of Growth Family, Member 3 (ING3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ING3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ING3 anticorps

Épitope: AA 1-92

Séquence: MLYLEDYLEM IEQLPMDLRD RFTEMREMDL QVQNAMDQLE QRVSEFFMNA KKNKPEWREE QMASIKKDYY KALEDADEKV QLANQIYDLQ HF

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-92 of human ING3 (NP_938008.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ING3

Antigène: ING3 (Inhibitor of Growth Family, Member 3 (ING3))

Autre désignation: ING3

Sujet: The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed.,ING3,Eaf4,ING2,MEAF4,p47ING3,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,ING3

Poids moléculaire: 11 kDa/46 kDa

ID gène: 54556

UniProt: Q9NXR8