CBR1 anticorps
Aperçu rapide pour CBR1 anticorps (ABIN614308)
Antigène
Voir toutes CBR1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- The antibody recognizes human CBR1. Other species not tested.
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Purification
- Protein-G affinity chromatography
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Isotype
- IgG2a
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.0 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- CBR1 (Carbonyl Reductase 1 (CBR1))
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Autre désignation
- Carbonyl Reductase 1
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Sujet
- Carbonyl reductase 1 (CBR1) is a NADPH-dependent, monomeric, and cytosolic enzyme belonging to a family of short-chain dehydrogenases/reductases. This protein consists of 277 amino acid residues and is widely distributed in human tissues such as liver, epidermis, stomach, small intestine, kidney, neuronal cells, and smooth muscle fiber. CBR1 metabolizes many toxic environmental quinones and pharmacological relevant substrates such as the anticancer drug, doxorubicin. The best substrates of CBR1 are quinones, including ubiquinone-1 and tocophrolquinone (vitamin E).Synonyms: 15-hydroxyprostaglandin dehydrogenase [NADP+], CBR, CBR1, CRN, NADPH-dependent carbonyl reductase 1, Prostaglandin 9-ketoreductase, Prostaglandin-E(2) 9-reductase
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ID gène
- 873
Antigène
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