AKR1C1 / DHH1 anticorps

N° du produit ABIN614310

Cet anticorps anti-AKR1C1 / DHH1 Monoclonal Souris (Clone AT6D10) (ABIN614310) détecte spécifiquement AKR1C1 / DHH1 dans EIA, IHC (p) et WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour AKR1C1 / DHH1 anticorps (ABIN614310)

Antigène: AKR1C1 / DHH1

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Application: Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Clone: AT6D10

Détail du produit

Specificité: The antibody recognizes Human AKR1C1. Other species not tested.

Purification: Protein-G affinity chromatography

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Détail du antigène

Antigène: AKR1C1 / DHH1

Sujet: The human aldo-keto reductases 1C1 and 1C3 (AKR1C1 and AKR1C3) have major roles in pre receptor regulation of progesterone action. They can both convert progesterone to the less potent efficiencies. AKR1C1 and AKR1C3 also act as 3-ketosteroid reductase, and as such they can convert the most potent androgen 5alpha-DHT into 3beta-andorstandiol, which is an estrogen receptor beta ligand, and into the inactive androgen 3alpha-androstnionl, respectively.Synonyms: 2-dihydrobenzene-1, 2-diol dehydrogenase, 20-alpha-hydroxysteroid dehydrogenase, Aldo-keto reductase family 1 member C1, Chlordecone reductase homolog HAKRC, Dihydrodiol dehydrogenase 1/2, High-affinity hepatic bile acid-binding protein, Trans-1

ID gène: 1645