LIN28A anticorps (AA 142-209)

N° du produit ABIN6143238

Cet anticorps Lapin Polyclonal détecte spécifiquement LIN28A dans WB, IHC et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour LIN28A anticorps (AA 142-209) (ABIN6143238)

Antigène: LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LIN28A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-LIN28A anticorps

Épitope: AA 142-209

Séquence: CGGLDHHAKE CKLPPQPKKC HFCQSISHMV ASCPLKAQQG PSAQGKPTYF REEEEEIHSP TLLPEAQN

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 142-209 of human LIN28 (NP_078950.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:1000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur LIN28A

Antigène: LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))

Autre désignation: LIN28A

Sujet: This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues.,LIN28A,CSDD1,LIN-28,LIN28,ZCCHC1,lin-28A,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Neuroscience,Stem Cells,Embryonic Stem Cells,LIN28A

Poids moléculaire: 22 kDa

ID gène: 79727

UniProt: Q9H9Z2

Pathways: Stem Cell Maintenance