LITAF anticorps (AA 1-161)

N° du produit ABIN6143254

Cet anticorps anti-LITAF est un anticorps Lapin Polyclonal détectant LITAF dans WB, IHC et IP. Adapté pour Humain.

Aperçu rapide pour LITAF anticorps (AA 1-161) (ABIN6143254)

Antigène: LITAF (Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LITAF est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Détail du produit anti-LITAF anticorps

Épitope: AA 1-161

Séquence: MSVPGPYQAA TGPSSAPSAP PSYEETVAVN SYYPTPPAPM PGPTTGLVTG PDGKGMNPPS YYTQPAPIPN NNPITVQTVY VQHPITFLDR PIQMCCPSCN KMIVSQLSYN AGALTWLSCG SLCLLGCIAG CCFIPFCVDA LQDVDHYCPN CRALLGTYKR L

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-161 of human LITAF (NP_004853.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:100

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur LITAF

Antigène: LITAF (Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))

Autre désignation: LITAF

Sujet: Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppressor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene.,LITAF,PIG7,SIMPLE,TP53I7,Epigenetics & Nuclear Signaling,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Growth factor,TNF,LITAF

Poids moléculaire: 15 kDa/17 kDa/23 kDa

ID gène: 9516

UniProt: Q99732

Pathways: Cellular Response to Molecule of Bacterial Origin