LY6E anticorps (AA 21-101)
Aperçu rapide pour LY6E anticorps (AA 21-101) (ABIN6143391)
Antigène
Voir toutes LY6E AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 21-101
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Séquence
- LMCFSCLNQK SNLYCLKPTI CSDQDNYCVT VSASAGIGNL VTFGHSLSKT CSPACPIPEG VNVGVASMGI SCCQSFLCNF S
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Réactivité croisée
- Humain, Souris
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 21-101 of human LY6E (NP_002337.1).
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Isotype
- IgG
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Indications d'application
- WB,1:1000 - 1:2000,IF,1:50 - 1:200
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Commentaires
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- LY6E (Lymphocyte Antigen 6 Complex, Locus E (LY6E))
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Autre désignation
- LY6E
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Sujet
- GPI-anchored cell surface protein that regulates T-lymphocytes proliferation, differentiation, and activation. Regulates the T-cell receptor (TCR signaling by interacting with component CD3Z/CD247 at the plasma membrane, leading to CD3Z/CD247 phosphorylation modulation (By similarity. Restricts the entry of human coronaviruses, including SARS-CoV, MERS-CoV and SARS-CoV-2, by interfering with spike protein-mediated membrane fusion. Plays also an essential role in placenta formation by acting as the main receptor for syncytin-A (SynA. Therefore, participates in the normal fusion of syncytiotrophoblast layer I (SynT-I and in the proper morphogenesis of both fetal and maternal vasculatures within the placenta. May also act as a modulator of nicotinic acetylcholine receptors (nAChRs activity (By similarity.,LY6E,RIG-E,RIGE,SCA-2,SCA2,TSA-1,LY6E
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Poids moléculaire
- 13 kDa
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ID gène
- 4061
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UniProt
- Q16553
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Pathways
- Hormone Transport
Antigène
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