MCM8 anticorps (AA 591-840)
Aperçu rapide pour MCM8 anticorps (AA 591-840) (ABIN6143648)
Antigène
Voir toutes MCM8 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 591-840
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Séquence
- FILLDTPNEH HDHLLSEHVI AIRAGKQRTI SSATVARMNS QDSNTSVLEV VSEKPLSERL KVVPGETIDP IPHQLLRKYI GYARQYVYPR LSTEAARVLQ DFYLELRKQS QRLNSSPITT RQLESLIRLT EARARLELRE EATKEDAEDI VEIMKYSMLG TYSDEFGNLD FERSQHGSGM SNRSTAKRFI SALNNVAERT YNNIFQFHQL RQIAKELNIQ VADFENFIGS LNDQGYLLKK GPKVYQLQTM
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Réactivité croisée
- Humain
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 591-840 of human MCM8 (NP_115874.3).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))
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Autre désignation
- MCM8
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Sujet
- The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the mini-chromosome maintenance proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the mini-chromosome maintenance proteins. The encoded protein may interact with other mini-chromosome maintenance proteins and play a role in DNA replication. This gene may be associated with length of reproductive lifespan and menopause. Alternatively spliced transcript variants encoding distinct isoforms have been described.,MCM8,C20orf154,POF10,dJ967N21.5,Epigenetics & Nuclear Signaling,MCM8
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Poids moléculaire
- 88 kDa/91 kDa/93 kDa/97 kDa
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ID gène
- 84515
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UniProt
- Q9UJA3
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Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
Antigène
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