NAD-ME anticorps (AA 220-479)
Aperçu rapide pour NAD-ME anticorps (AA 220-479) (ABIN6143674)
Antigène
Voir toutes NAD-ME AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 220-479
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Séquence
- GLYQKRDRTQ QYDDLIDEFM KAITDRYGRN TLIQFEDFGN HNAFRFLRKY REKYCTFNDD IQGTAAVALA GLLAAQKVIS KPISEHKILF LGAGEAALGI ANLIVMSMVE NGLSEQEAQK KIWMFDKYGL LVKGRKAKID SYQEPFTHSA PESIPDTFED AVNILKPSTI IGVAGAGRLF TPDVIRAMAS INERPVIFAL SNPTAQAECT AEEAYTLTEG RCLFASGSPF GPVKLTDGRV FTPGQGNNVY IFPGYRIPIC
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Réactivité croisée
- Humain, Souris
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 220-479 of human ME2 (NP_001161807.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IP,1:50 - 1:200
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Commentaires
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- NAD-ME (NAD Dependent Malate Dehydrogenase (NAD-ME))
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Autre désignation
- ME2
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Sujet
- This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene.,ME2,ODS1,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Warburg Effect,ME2
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Poids moléculaire
- 53 kDa/65 kDa
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ID gène
- 4200
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UniProt
- P23368
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Pathways
- Production of Molecular Mediator of Immune Response
Antigène
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